Control of gene expression and early development in Drosophila melanogaster

The goal of our research is to understand how genetic regulatory mechanisms impact on the elaboration of developmental pathways-- how are developmental pathways chosen and how is this choice of a pathway subsequently remembered. We have examined the mechanisms controlling pathway choice and pathway maintenance in three different D. melanogaster developmental systems.

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• Chromosome Structure and Gene Expression
• Oocyte Specification and Orb
• Formation of the Embryonic Gonad
  • PGC Migration
  • Oocyte Specification
• 2001/2002 Controversy